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Euro Medicinal Chemistry 2019

About Conference


Following the overwhelming success of Conference held in several European, Asian, South African Countries and USA, the Organizing Committee of Conference Series LLC LTD is pleased to invite all the participants across the globe to attend the International Conference on Medicinal Chemistry scheduled to be held on February 26-28, 2019 at Paris, France.

The primary focus of this meeting is the exploration of fundamental principles of contemporary medicinal chemistry. Speakers will share useful strategies for optimizing the pharmacological, toxicological, and metabolic profiles of drug leads and candidates. Sessions will focus on the modern technologies used to accelerate industrial drug discovery programs. This symposium is organized in a workshop format, allowing for close interaction between practicing medicinal chemists and participating attendees. Case studies of drug discovery projects will highlight successful approaches taken to deliver clinical candidates. In addition to this, all the inter-related fields of medicinal chemistry will also be discussed at the conference.

The above being as our core concept ever since, the entire our program was tailored year after year which includes the prompt keynote presentations, Oral talks, Workshops, Poster presentations, Video Presentations and Exhibitions.

Euro Medicinal Chemistry 2019 is a global platform to discuss and learn about Medical research Advances in Medicinal Chemistry, Bioorganic and Medicinal Chemistry, Contemporary trends in Drug Design and Drug Development, Computational Chemistry, Organic Chemistry, Analytical Chemistry, Chemical Biology, Anticancer agents in Medicinal Chemistry, Pharmaceutical Formulations, Synthetic Chemistry, CADD (Computer Aided Drug Design). Euro Medicinal Chemistry 2019 will gather the world class experts both of Medicinal Chemistry from both academic and industry to a common platform.

For abstract submission kindly click the following link:  https://medicinalchemistry.annualcongress.com/abstract-submission.php

Conferenceseries LLC LTD organises 800+ Conferences every year across USA, Europe & Asia with support from 1000 more scientific societies and publishes 400+ Open access journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Motives to Attend:

  • Keynote presentation along with interactions to galvanize the scientific community.
  • Workshop and symposiums to reach the largest assemblage of participants from the Pharma and Chemistry community.
  • A wide track of exhibitors to showcase the new and emerging technologies.
  • Platform to global investment community to connect with stakeholders in Pharma and Chemistry sector.
  • Young Scientist/ Investigators Award geared towards best budding young research.
  • Links to the political marketing resources to expand your business and research network.
  • Triumph of Awards, Certificates recognizes your commitment to your profession to encourage the nascent research.

Target Audience:

  • Scientists and Researchers
  • Directors, CEO’s of Pharmaceutical and Chemical Organizations
  • Scholars from Pharmacology, Pharmaceutical, Toxicology backgrounds
  • PhD Scholars
  • Drug Delivery Technology Manufacturers
  • Business Development Managers
  • Distributors and Suppliers of Drug Delivery Technologies
  • Students, Professors, Researchers, and Faculty of Medicinal Chemistry & Pharmaceutical Sciences from Universities and Medical Colleges
  • Researchers from Pharmaceutical Companies, Pharmacy, Pharmacology & Chemical Associations and Societies
  • Health professionals
  • Pharmacists, Pharmacologists, & Toxicologists
  • Business development professionals, Consultants, Pharma, and Toxicology Testing service providers
  • Quality control specialists
  • Graduates and post graduates in industrial pharmacy
  • Medical Devices Manufacturing Companies, CRO
  • Data Management Companies.
  • Pharmaceutical legislators and regulators
  • Drug Delivery Companies & Organizations

Sessions and Tracks

Track 01: Emerging Drug Targets:

In the early days of drug discovery, medicinal chemists often optimized and developed compounds without much knowledge of the drug target or pathway in mind. Modern technologies have had an enormous impact on drug discovery since the mid-20th century. The early influence of experimental pharmacology, which was first employed to study drug side-effects, coupled with advances in cell biochemistry led to the identification of many enzymes and receptors as new drug targets, thus enabling medicinal chemists to develop compounds to interact selectively with targets for a wide range of therapeutic areas. Medicinal chemistry therefore has fully-fledged to comprehend a wider range of scientific disciplines in the process of drug discovery, there by leading to minimize the cost of drug development, the time during the process of development and the risks of drug development.

Sub Tracks: 

  • Targeted Protein Degradation
  • DNA Encoded Libraries
  • Hit-to-Lead Optimization
  • Predictive Toxicology – Improving Compound Safety
  • Optimizing Outsourcing Activities
  • Artificial Intelligence in Medicinal Chemistry
  • Small Molecule Immuno-Oncology

Related Conferences: Medicinal Chemistry Conferences | Medicinal Chemistry 2018 | International Chemistry Conferences | Medicinal Chemistry Meetings | Medicinal Chemistry Events | Chemistry Conferences | Chemistry Meetings | Chemistry Congress | Drug Events

Track 02: Drug Discovery Chemistry:

The discovery of candidate drug targets is challenging, requiring the rapid development of techniques to identify the difference genomic profiling in disease and normal conditions, which will facilitate the understanding of the disease mechanism and the development of potential drugs for disease treatment. Medicinal chemistry has increasingly employed microarrays to identify both key target genes and gene networks that can regulate the effectiveness of drugs. As compared with all the other phases in drug discovery, this stage is complex by the fact that the identified drug target must mollify a variety of standards to permit development to the next step. For example, the target must be selectively present in the pathogen, i.e. medicinal chemistry along with coding genes of drug design target that are preserved across different pathogens and have no human homologs and therefore they represent striking target candidates for new broad-spectrum drugs.

Sub Tracks:

  • Fragment-Based Drug Discovery
  • Macrocyclics & Constrained Peptides
  • Biophysical Approaches for Drug Discovery
  • Small Molecules for Cancer Immunotherapy
  • Inflammation Inhibitors
  • Protein-Protein Interactions
  • GPCR-Targeted Drug Design
  • Blood-Brain Penetrate Inhibitors
  • Kinase Inhibitor Chemistry

Related Conferences: Medicinal Chemistry Conferences | Medicinal Chemistry 2018 | International Chemistry Conferences | Medicinal Chemistry Meetings | Medicinal Chemistry Events | Chemistry Conferences | Chemistry Meetings | Chemistry Congress | Drug Discovery Conferences

Track 03: Chemogenomics:

Chemogenomics is an emergent discipline that combines the latest tools of genomics and chemistry and applies in the discovery of novel drug molecules thereby to target drug discovery. Because of the almost infinite number of drug-like organic molecules, this is an impossible task. Chemogenomics, on the other hand can be defined as the investigation of classes of compounds or related libraries. These compounds are meant to work against families of functionally related proteins in the protein structure. Chemogenomics also deals with the chemical-biological interactions and their systematic analysis.

Sub Tracks:

  • Biomolecules
  • Preparation of Natural products
  • Metal Complexes creation
  • Asymmetric synthesis
  • Organometallic chemistry
  • Nucleotide chemistry
  • Chemogenomics and Chemical Biology for Target Identification and Validation
  • Assemblies of macrolide-mimetics
  • Spiro– medium- and large(macro) heterocyclic systems
  • Isosteric replacements of amino acids, di-/tri-peptides

Related Conferences: Medicinal Chemistry Conferences | Medicinal Chemistry 2018 | International Chemistry Conferences | Medicinal Chemistry Meetings | Medicinal Chemistry Events | Chemistry Conferences | Chemistry Meetings | Chemistry Congress | Chemogenomics Conferences

Track 04: Medicinal Chemistry Strategies:

In the drug discovery and drug development of a new drug, different terms are assigned to the substances that are studied at different steps in the process. Only if a substance fulfills the requirements for a certain level is it subjected to testing on the next level. The process starts with a compound which is a chemical substance of defined chemical structure and purity. There are many strategies developed in Medicinal Chemistry in the recent years for the development of new drug candidates. Compounds that show specific binding properties and are active are referred to as ‘hits’ and are further validated; this includes verifying their chemical identity and purity and determining their binding properties in one or more secondary assays.

Sub Tracks:

  • ADCs – Targeted delivery
  • Immuno-oncology
  • Small-molecule targeting of RNAs
  • Preventative Toxicology
  • Molecules with predictable in vivo and safety profiles
  • Phenotypic screening
  • SBDD Case studies
  • Macrocyclic compounds

Related Conferences: Medicinal Chemistry Conferences | Medicinal Chemistry 2018 | International Chemistry Conferences | Medicinal Chemistry Meetings | Medicinal Chemistry Events | Chemistry Conferences | Chemistry Meetings | Chemistry Congress | Medicinal Chemistry Symposiums

Track 05: CADD (Computer Aided Drug Design):

Computational methods of drug design are based on a postulate that pharmacologically active compounds act by interaction with their macromolecular targets, mainly proteins or nucleic acids. Major factors of such interactions are surfaces of molecules, electrostatic force, hydrophobic interaction and hydrogen bonds formation.  The channel of drug discovery from idea to market consists of seven basic steps: disease selection, target selection, lead compound identification, lead optimization, pre-clinical trial testing, clinical trial testing and pharmacogenomic optimization. In practice, the last five steps required to pass repeatedly.

Sub Tracks:

  • Receptor theory
  • Molecular Modeling and Computational Chemistry
  • Quantum Mechanics and Molecular Mechanics
  • Steepest Descent Method
  • Conjugate Gradient Method
  • Structure-Based Computer-Aided Drug Design
  • Ligand-Based Computer-Aided Drug Design
  • Molecular Docking
  • Database Searching
  • de novo Drug Design

Related Conferences: Medicinal Chemistry Conferences | Medicinal Chemistry 2018 | International Chemistry Conferences | Medicinal Chemistry Meetings | Medicinal Chemistry Events | Chemistry Conferences | Chemistry Meetings | Chemistry Congress | CADD Events

Track 06: Bioanalytical Sciences and Organic Synthesis:

Bioorganic chemistry involves the study of biological processes using chemical methods. Organic chemistry methods are used to synthesize biological molecules and to examine their structure, to investigate biochemical reactions. In synthetic organic chemistry the synthesis is implying to the aspect of a planned sequent route resulting in products with desired activity.

Sub Tracks:

  • Bioanalytical Techniques
  • Hyphenated Techniques
  • Chromatography Methods
  • Electrophoresis
  • Ligand Binding Assays
  • Mass Spectrometry
  • Nuclear Magnetic Resonance
  • Sample preparation and extraction
  • Natural Products Synthesis
  • Synthetic methodology
  • Catalysis
  • New synthetic technologies
  • Medicinal Chemistry and Chemical Biology
  • Synthesis of nano and functionalized Materials

Related Conferences: Medicinal Chemistry Conferences | Medicinal Chemistry 2018 | International Chemistry Conferences | Medicinal Chemistry Meetings | Medicinal Chemistry Events | Chemistry Conferences | Chemistry Meetings | Chemistry Congress | Organic Chemistry Conferences | Bioanalytical Conferences

Track 07: Enabling Technologies of Medicinal Chemistry:

Modern drug research and development (R&D) has experienced remarkable changes as technological and scientific developments in the past years have dramatically changed the pharmaceutical innovation process. Well-established strategies, such as high-throughput screening (HTS), have progressively been applied in association with novel techniques founded on genomics, molecular and structural biology and molecular modeling.

Sub Tracks:

  • Targeted protein degradation / PROTACs
  • DNA Encoded Libraries
  • Hit-to-Lead Optimization
  • Predictive Toxicology – Improving Compound Safety
  • Optimizing Outsourcing Activities
  • Artificial Intelligence in Medicinal Chemistry

Related Conferences: Medicinal Chemistry Conferences | Medicinal Chemistry 2018 | International Chemistry Conferences | Medicinal Chemistry Meetings | Medicinal Chemistry Events | Chemistry Conferences | Chemistry Meetings | Chemistry Congress | Medicinal Chemistry Technologies

Track 08: Integrating Medicinal Chemistry into the Drug Discovery Process:

Traditionally, “drug delivery” was a specialization in pharmacy for formulations of drugs. However, it is natural that organic, medicinal, materials, and nano chemistry have now become deeply involved in the development of drug delivery systems. These approaches have led to the creation of drug conjugates that are new chemical entities. The use of functional carbon nanotubes as well as designed polymers as a vehicle for drug delivery is a novel approach to drug discovery.

Sub Tracks:

  • Drug Discovery Chemistry – where are we heading
  • Target Validation using Medicinal Chemistry tools
  • Optimizing hit to lead optimization quality and timescale
  • Best Practice Case Studies
  • Data for decision making
  • Protein Degradation Strategies
  • Future of Medicinal Chemistry

Related Conferences: Medicinal Chemistry Conferences | Medicinal Chemistry 2018 | International Chemistry Conferences | Medicinal Chemistry Meetings | Medicinal Chemistry Events | Chemistry Conferences | Chemistry Meetings | Chemistry Congress | Drug Discovery Conferences

Track 09: Medicinal Chemistry Advances

The main objective of medicinal chemistry has always been and still is to identify new compounds which can be used as the active principle of effective and safe medicines. The recent advances of medicinal chemistry include target classes i.e., receptors, transporters, enzymes, regulatory proteins, target-ligand interactions, structure activity relationship (SAR) studies, structure and ligand based drug design, point of action and the prodrug concept, peptidomimetics and protein based drugs, drugability of lead compounds, experimental methods in biological and biostructural chemistry, basic and advanced medicinal chemistry concepts, and also the recent concept of 3D modeling of protein structure and ligand docking.

Sub Tracks:

  • Kinase Inhibitors
  • Approaches to Optimization and Characterization
  • Inhibitors for Rare Diseases
  • Recent Advances in Screening Approaches to Lead Identification
  • Novel Approaches to Anti-Infective Drug Discovery and Liver Disease
  • Targeting RNA
  • Macrocycles in Drug Design
  • Advances in Targeting Immuno-Inflammation
  • Synthesis Applications and ADME in Drug Discovery

Related Conferences: Medicinal Chemistry Conferences | Medicinal Chemistry 2018 | International Chemistry Conferences | Medicinal Chemistry Meetings | Medicinal Chemistry Events | Chemistry Conferences | Chemistry Meetings | Chemistry Congress | Advanced Medicinal Chemistry Events

Track 10: Drug Design and Synthesis:

The rational development of new drugs is a complex process involving a myriad of different disciplines. In nearly all of these, computational tools serve to guide the design decisions, ultimately speeding up and reducing the cost of development.2 In the area of medicinal chemistry, computational methods are applied both to identify new starting points and to guide the further development of promising substances.

Sub Tracks:

  • Frontiers in Catalysis
  • Aggressive Bond Disconnections in Total Synthesis
  • Chemical Probes for Characterizing Biology
  • Synthetic Biology for Natural Products
  • Advances in Drug Discovery
  • Natural Product Discovery and Biosynthesis
  • Combining Synthesis and Biosynthesis to Construct Complex Molecules
  • New Directions in Antibiotic Discovery and Development
  • Accessing Complex Molecules
  • Structure-biodegradability relationship
  • Diversity-Oriented Synthesis

Related Conferences: Medicinal Chemistry Conferences | Medicinal Chemistry 2018 | International Chemistry Conferences | Medicinal Chemistry Meetings | Medicinal Chemistry Events | Chemistry Conferences | Chemistry Meetings | Chemistry Congress | Drug Design Conferences

Track 11: Organic Chemistry:

The synthesis of each molecule was first carried out on a small scale (probably milligrams) in the laboratory, followed much later by development of safe, efficient, and scalable methods to provide kilograms of active pharmaceutical ingredient (API) that was incorporated into dosage forms for administration to patients. It is critical to point out that an early step in the complex process of drug discovery was the synthesis of a molecule that tested a hypothesis faced by the project team. This required a medicinal chemist to use organic chemistry training and experience to conceive of a compound and then employ appropriate reactions to furnish the desired target and synthesize a suitable number of derivatives to optimize the spectrum of properties associated with drug like candidates.

Sub Tracks:

  • Medicinal chemistry
  • Drug discovery
  • Total synthesis of natural products
  • Heterocyclic compounds
  • Synthesis and functional properties of molecules
  • Asymmetric synthesis
  • Green chemistry
  • New reagents, strategies, catalysts and concepts for organic synthesis
  • Mechanistic organic chemistry
  • Computational chemistry
  • Supramolecular chemistry

Related Conferences: Medicinal Chemistry Conferences | Medicinal Chemistry 2018 | International Chemistry Conferences | Medicinal Chemistry Meetings | Medicinal Chemistry Events | Chemistry Conferences | Chemistry Meetings | Chemistry Congress | Organic Chemistry Conferences

Track 12: Chemical Synthesis and Catalysis:

From drug synthesis to quality control (QC) monitoring of over-the-counter medications, metals are found in all phases of the drug development process. Many metal-based products are used as imaging agents, and metals are used in the synthesis of drug substances, as excipients in tablets, capsules and liquids. In addition, trace metals can arise from the equipment used to manufacture a drug substance or compound. Because of the prevalence of metals associated with the drug development and manufacturing process, various atomic and emission-based techniques are often used to help fully characterize pharmaceutical products.

Sub Tracks:

  • Organocatalysis
  • Flow-chemistry approaches to the synthesis of key targets
  • Applications of organometallic compounds in synthesis and catalysis
  • Stereoselective synthesis
  • Synthesis and property of functional molecules and organic materials
  • Sustainable and Green synthetic and catalytic methods
  • Process development of key pharmaceutical targets
  • Synthesis in Medicinal chemistry and chemical biology
  • Biocatalysis in synthesis
  • Computational tools for synthesis and catalysis
  • Polymer synthesis

Related Conferences: Medicinal Chemistry Conferences | Medicinal Chemistry 2018 | International Chemistry Conferences | Medicinal Chemistry Meetings | Medicinal Chemistry Events | Chemistry Conferences | Chemistry Meetings | Chemistry Congress | Drug Monitoring Conferences

Track 13: Synthetic Chemistry;

Synthetic Organic Chemistry is designed to summarize in a single volume method of organic syntheses most dependently employed in the preparation of mono- and di-functional compounds. The methods are collected in chapters each of which is &voted to the formation of compounds containing a functional group or related groups.

  • Addressing Preclinical Toxicity
  • Advances in Lead Generation
  • Advances in Synthetic Methods
  • Alternative Modalities
  • Challenges and Opportunities in Fragment Based Drug Discovery
  • Chemical Biology in Drug and Target Discovery
  • Drug Discovery Tales
  • Late Stage Functionalization
  • High pressure cryogenic reactions
  • Enzymatic reactions
  • Cascade addition-cyclization
  • Multi-component reactions
  • One-pot Syntheses

Sub Tracks:

Related Conferences: Medicinal Chemistry Conferences | Medicinal Chemistry 2018 | International Chemistry Conferences | Medicinal Chemistry Meetings | Medicinal Chemistry Events | Chemistry Conferences | Chemistry Meetings | Chemistry Congress | Synthetic Chemistry Conferences

Track 14: Biorganic Chemistry

Broadly defined, the discipline of bioorganic chemistry seeks an understanding of biological processes through the tools and principles of organic chemistry. Biorganic chemistry can be defined as a multifaceted field which has its historical roots in detailed mechanistic studies of enzyme along with coenzyme models. The field of bioorganic chemistry currently focuses more on the trending topics like molecular recognition, encompassing mechanistic investigations of enzymes themselves, drug design. It also deals with study of drug action, problems in biosynthesis, protein engineering, molecular evolution, supramolecular chemistry, and many other allied subjects.

Sub Tracks:

  • Structural and in-Silico Chemistry
  • Chemical Biology for Drug Discovery
  • Pain Medications and their SAR
  • Recent Advances in Targeting Autophagy
  • Advances in Synthesis and Medicinal Chemistry
  • Photo-redox Catalysis

Related Conferences: Medicinal Chemistry Conferences | Medicinal Chemistry 2018 | International Chemistry Conferences | Medicinal Chemistry Meetings | Medicinal Chemistry Events | Chemistry Conferences | Chemistry Meetings | Chemistry Congress | Bioorganic Chemistry Conferences

Track 15: Pharmaceutical Formulation

Formulation development is a key area of product development that can determine patentability, lifecycle and, ultimately, the success of a pharmaceutical product. Companies integrate formulation development functions and personnel into their product development cycle in many ways. In fully integrated large pharmaceutical companies, specific departments may exist to deal with such areas as the physical characterization of drug substances and formulation issues.

Sub Tracks:

  • Design, manufacture and use of efficacious dosage forms
  • Types of Formulation: Enteral, Parenteral and Topical
  • Water-miscible formulations
  • Other formulations
  • Pesticide formulation
  • Recent Developments in Dosage Form Design
  • Establishing the Bioequivalence of Pharmaceutical Products

Related Conferences: Medicinal Chemistry Conferences | Medicinal Chemistry 2018 | International Chemistry Conferences | Medicinal Chemistry Meetings | Medicinal Chemistry Events | Chemistry Conferences | Chemistry Meetings | Chemistry Congress | Pharmaceutical Chemistry Conferences | Pharmaceutical Conferences

Track 16: Applications of ADME in Drug Discovery:

The sighting of new drugs molecules can be mainly classified into two main stages divided into two stages i.e., the discovery of the drug molecule and then the development of the same. Drug discovery includes producing a hypothesis of the target receptor for a specific disease or disorder. This also includes the screening of the in vitro and/or the in vivo biological activities of the new drug candidates or the new drug profiles that are being developed. Drug development involves the assessment of efficacy and toxicity of the new drug candidates. Pharmacokinetic data provides all the information regarding the drug candidates that can guide future animal and clinical studies for the selection of the dose levels and thereby helps us to know the frequency of administration.

Sub Tracks:

  • ADME (adsorption, distribution, metabolism and excretion)Of drugs
  • Metabolism and toxicology
  • Antiviral and antimicrobial activity
  • Drug receptor interaction
  • Kojic acid as a tyrosine inhibitor
  • Components of ADME
  • Pharmacokinetics and process of ADME

Related Conferences: Medicinal Chemistry Conferences | Medicinal Chemistry 2018 | International Chemistry Conferences | Medicinal Chemistry Meetings | Medicinal Chemistry Events | Chemistry Conferences | Chemistry Meetings | Chemistry Congress | Drug Delivery Conferences

Track 17: Analytical Chemistry:

Analytical chemistry helps in facilitating the investigation of biological targets and drug metabolism. The field of analytical chemistry helps us to provide the new insights into how molecular properties affect biological profile of the drug candidates and to underpin the biotherapeutic approaches like purification, quality assurance of the discovered drug molecules. Techniques for biomarker identification and detection and probe design (mass spectrometry, PET, SPECT, MRI, labelling). Biophysical techniques for screening and target validation.

Related Conferences: Medicinal Chemistry Conferences | Medicinal Chemistry 2018 | International Chemistry Conferences | Medicinal Chemistry Meetings | Medicinal Chemistry Events | Chemistry Conferences | Chemistry Meetings | Chemistry Congress | Analytical Chemistry Conferences

Sub Tracks:

  • Analytical Techniques for Clinical Chemistry
  • Chemical Analysis
  • Electrochemical Analysis
  • Spectroscopy
  • Separation Techniques

Track 18: Pharmaceutical Industry:

Medicinal chemistry as a discipline is alive and well in both academic and industrial quarters. However, is it making the same kind of impact that was witnessed in the golden era of drug discovery, estimated as 1975–2000? In the first half of that period, the marriage of the medicinal chemist and the pharmacologist was a key driving force for a research project, often leading to useful, new medicines. The scientific prowess, creativity, insight and intuition of these researchers were crucial attributes for success. As the drug-discovery process became increasingly complex and ponderous, and as modern technologies entered the picture, the chemist–pharmacologist axis, so to speak, became increasingly diluted.

Sub Tracks:

  • Foundation in Paediatric Pharmaceutical Care
  • Equipment and Technologies for the Pharmaceutical Industry
  • Validation & Transfer of Methods for Biopharmaceutical Analysis
  • Stability and Shelf-life of Pharmaceuticals
  • Pharmaceutical Microbiology
  • Corporate Compliance & Transparency in the Pharmaceutical Industry

Related Conferences: Medicinal Chemistry Conferences | Medicinal Chemistry 2018 | International Chemistry Conferences | Medicinal Chemistry Meetings | Medicinal Chemistry Events | Chemistry Conferences | Chemistry Meetings | Chemistry Congress | Pharmaceutical Conferences | Pharma Meetings | Pharma Events

Track 19: Pharmacology and Toxicology:

Safety pharmacology studies are applied to marketed pharmaceuticals when adverse clinical events occur. It is applied for a new patient population and when a new route of administration raises concerns not previously addressed. In the design of toxicology, kinetic and clinical studies, some safety pharmacology endpoint can be incorporated.

Toxicology studies the interaction between biological systems and chemicals to determine the adverse effects in organisms that are caused by the potential of chemicals. Toxicology can be defined as the study of the adverse effects of chemicals, pharmaceutical chemicals or any other physical agents on living organisms. They may occur at various levels within the body, from cellular level to organ level and can affect the organism or sometimes a specific biochemical.

  • Rational Prescribing
  • Adverse drug effects
  • Drug interactions
  • Drug Development
  • Pharmacogenomics
  • Structure-guided Drug Design
  • Molecular Cloning of Drug Targets
  • Cellular Basis of Pharmacokinetics
  • Cellular Basis of Pharmacokinetics
  • Receptors and Modulation of Their Response
  • Drug–Receptor Interactions
  • G-Protein-Coupled Receptors
  • Pharmacology of Transcription
  • Intercellular communication
  • Pharmacology of defense process

Sub Tracks:

Related Conferences: Medicinal Chemistry Conferences | Medicinal Chemistry 2018 | International Chemistry Conferences | Medicinal Chemistry Meetings | Medicinal Chemistry Events | Chemistry Conferences | Chemistry Meetings | Chemistry Congress | Pharmacology Conferences | Toxicology Conferences

Track 20: Organic and Medicinal Chemistry Technologies for Drug Discovery:

The recent changes in the way that synthetic chemistry is practiced in this environment center around new scientific advances in synthetic techniques and modern technologies for rational drug design, combinatorial chemistry, automated synthesis, and compound purification and identification. In addition, with the beginning of high-throughput screening, we are now dealing with many targets being screened and many other hits that are being evaluated. However, success in the discovery of new drug molecules requires more and more skilled medicinal chemists to make the accurate choices with the insights gathered from interactions with computational chemists along with the insights from structural biologists, about which “hits” are likely to play out as true “lead” structures that will meet the plethora of hurdles that any drug candidate must surmount.

Sub Tracks:

  • Virtual Screening
  • Target Structure-Based Design
  • QSAR (Quantitative Structure-Activity Relationship)
  • Fragment-Based Drug Design

Related Conferences: Medicinal Chemistry Conferences | Medicinal Chemistry 2018 | International Chemistry Conferences | Medicinal Chemistry Meetings | Medicinal Chemistry Events | Chemistry Conferences | Chemistry Meetings | Chemistry Congress | Organic Chemistry Conferences | Pharmaceutical Chemistry Conferences

Market Analysis

Importance & Scope

Medicinal chemistry is a stimulating field as it links many scientific disciplines and allows for collaboration with other scientists in researching and developing new drugs.

Medicinal chemists apply their chemistry training to the process of synthesizing new pharmaceuticals. They also improve the processes by which existing pharmaceuticals are made. Medicinal chemists are focused on drug discovery and development and are concerned with the isolation of medicinal agents found in plants, as well as the creation of new synthetic drug compounds. Most chemists work with a team of scientists from different disciplines, including biologists, toxicologists, pharmacologists, theoretical chemists, microbiologists, and biopharmacists. Together, this team uses sophisticated analytical techniques to synthesize and test new drug products and to develop the most cost-effective and environmentally friendly means of production.

Medicinal Chemistry for Drug Discovery Market: Overview

Over the last decade, industry’s productivity has been declining with rising R&D costs and time taken to reach market. Medicinal chemistry is defined as a focused science that is developed to cover a wide range of fields related with identification, synthesis and drug development for therapeutic applications. This science has evolved from medical chemists focusing on drug target or pathway in mind and league of elaborative chemistry-driven processes to modern generation of high-throughput screening (HTS) libraries that are created by combinatorial chemistry based on few structural distinctions across large drug like scaffolds.

This change was needed because of high attrition rate in pre-clinical and incubation drug development studies because of earlier methods. While the primary task of medicinal chemists has not changed significantly over a period of time, the computational tools and chemicals and perspectives at their clearance or removal have advanced extensively.

The various tools of medicinal chemistry are in silico modeling, structure-based drug design (SBDD), comparative molecular field analysis (CoMFA) or 3D QSAR method. The fragment-based drug design promisingly stands out because of substantial improvements in research and productivity. One of the primary challenges of drug discovery is to design a robust drug that is both safe and effective in a wide range of population. The various drug designing types are structure-based drug design, natural products-based drug design, fragment-based drug design, diversity-oriented synthesis and chemogenomics.

Medicinal Chemistry for Drug Discovery Market: Trends

Due to modern technology an alternative approach to the large combichem libraries (10,000 plus molecules) is available, these are smaller focused arrays known as chemogenetic arrays that assists for confining of specific pharmacophore model for specific family to target but considering ADME and drug-like properties. The compound arrays must be synthetically feasible and to minimize the attrition rate in preclinical testing, must also consist of specific properties regarding adsorption, distribution, metabolism, elimination and toxicity (ADMET).

During this process the ADMET constraints established from information mining, in vitro and in vivo studies are often compiled into computational packages to enable chemists to predict the drug-likeliness of a compound.

The recent market trends observed with medicinal chemistry operations are outsourced by most of the pharmaceutical companies because this helps the companies to pace up the research process making it time and cost efficient. The outsourcing trend observed from the North American and European pharmaceutical companies to the companies of developing companies like India, China and Others from Asian continent.

Medicinal Chemistry for Drug Discovery Market: Opportunities and Competitive Dynamics

The mightiest challenge in this industry is to reduce the number of drugs that fail in pre-clinical stages, as this facilitates the manufacturer to enter the market with a high-priced drug. But since the ADME profiling used in silico and cellular approaches have successfully reduced the attrition rate. According to industry experts currently structure-based drug design has high acceptance followed by fragment-based variation, natural products, while diversity-oriented synthesis and chemogenomics have negligible market shares. The top five active therapeutic research areas are cancer, infections, neurological, gastrointestinal, endocrine and cardiovascular.

Drug discovery is expected to be largely practiced at small niche biopharmaceutical companies around the world in the U.K., U.S., Western Europe, Eastern Europe, China, India, Brazil, South Africa and Mexico as investments, time and risks are comparatively less in this operations model than the traditional. Overall the medicinal chemistry has improved all these years with all updated technologies and methodologies.

The importance of small and medium scaled companies will increase in this market as it will reduce the time and cost for a big pharmaceutical company. Hence, in drug discovery medicinal chemistry plays important role but still the accuracy and precision of the study needs to be improved to achieve minimum rejections in the preclinical studies. 

The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.

Past Conference Report

Medicinal Chemistry 2018

Conference Series LLC Ltd sincerely thanks all of our wonderful Speakers, Conference Attendees and Collaborators; Medicinal Chemistry 2018 Conference was our best ever!

10th World Congress on Medicinal Chemistry and Drug Design June 14-15, 2018 Barcelona, Spain hosted by Conference Series LLC Ltd was held during June 14-15, 2018 Barcelona, Spain at Holiday with the theme “Research on present and future techniques and development in Drug Design” which got splendid response. With the support and guidance of Organizing Committee Members and Editorial Board Members in the fields of Medicinal chemistry and materials science and astonishing presentations of all participants this prominent event became more impressive.

Conference Series LLC Ltd would like to convey a great appreciation to following eminent people, honourable guests and Keynote speakers.

Celerino Abad-Zapatero, University of Illinois at Chicago (UIC), USA

Franz-Josef Meyer-Almes, University of Applied Sciences Darmstadt, Germany

Barbara De Filippis, University “G. d’Annunzio”, Italy

Letizia Giampietro, University “G. d’Annunzio”, Italy

Vladimir Potemkin, South Ural State University, Russia

Maria Grishina, South Ural State University, Russia

C S Ramaa, Bharati Vidyapeeth’s College of Pharmacy, India

Conference Series LLC Ltd extends its gratitude towards Poster Judge Franz-Josef Meyer-Almes, University of Applied Sciences Darmstadt, Germany. We also congratulate our Best Poster awardees for their outstanding performances in the field of Medicinal Chemistry and appreciate all the participants who had put their efforts in poster presentations and sincerely wish them success in future endeavours.

Medicinal Chemistry 2018 Organizing Committee would like to thank the Moderator of the conference, Miss. Edita Sarukhanyan, University of  Würzburg , Germany who contributed a lot for the smooth functioning of this event.

Conference Series LLC Ltd also took privilege to felicitate the Keynote Speakers, Organizing Committee Members, Chairs and Co-chairs who supported this event.

With sustainable excitement for grand success of Medicinal Chemistry 2018, Conference Series LLC Ltd is glad to announce next annual meeting

International Conference on Medicinal Chemistry to be held during February 26-28, 2019 in Paris, France

We hope your favourable support will make next annual also one more grand success event.

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